GlycosBio develops new microbial platform

Texas-based Glycos Biotechnologies Inc. recently announced it has created a microbial technology platform that can convert fatty acids into ethanol, advanced biofuels and biochemcials. The new platform is similar to GlycosBio’s glycerin conversion technology, but targets a different, low-value feedstock.

“What we do is use metabolic engineering to design microorganisms that produce specific chemicals,” said Paul Campbell, GlycosBio’s chief science officer. “We do use E. coli, the traditional workhorse bacterial for most biotechnology, but we also use other microbial strains-ones that have a very strong history of use in industrial-scale fermentation.”

One significant benefit of GlycosBio’s new technology platform is that it produces high product yields. In the ethanol production process, one pound of sugar only creates about a half pound of fuel. “In the case of fatty acids, we’ve already demonstrated the one-to-one conversion, which would be the equivalent of taking one pound of fatty acid and making one pound of ethanol. Additional benefits of the technology include the ability to produce complex molecules, and the process does not require a highly purified feedstock, Campbell said.

While the platform is capable of producing renewable fuels, such as ethanol and biobutanol, Campbell said the long-term goal of his company is to produce biobased chemicals, including acetate, acetone, isopropanol, succinate and propionate from fatty acids